Molecular Biology of Protein Folding, Part A

The importance of protein folding has been recognized for many years. It is the underlying etiology in a large number of human diseases and it appears to be a novel method for cellular regulation of the expression of newly translated proteins. These volumes (Parts A & B) address this important topic. As a volume in Progress in Nucleic Acid Research and Molecular Biology, this book provides the latest information on the expanding research being conducted on protein folding. Illustrates how ubiquitin domain proteins are an ideal model system for experimental and computational studies of protein folding.Discusses structural wrapping and its importance in the contexts of network centrality, molecular disease, drug discovery and molecular theranostic engineering.Chapters written by international authors in engineering, biochemistry, physics, and computer science.